22nd September 1944: birth of Fraser Hines, who played Jamie from 1966 to 1969, and has appeared in more Doctor Who episodes than anyone except the first four Doctors.
22nd September 1982: birth of Billie Piper, who played Rose in the first two series of New Who (2005-06) and reappeared in 2008 and 2010; has appeared in more New Who episodes than anyone except David Tennant.
ii) broadcast anniversaries
22nd September 1979: broadcast of fourth episode of Destiny of the Daleks. The Doctor defeats first the Movellans and then the Daleks, and Davros is captured and taken away for trial.
iii) date specified in canon
22nd September 1960: birth of Tegan Jovanka, as revealed in the 2006 Big Finish adventure The Gathering.